We break down the key differences between traditional cigarettes and e cigarettescovering: 1 Their compositions and ingredients. 2 The health risks associated with both. 3 Nicotine levels and addiction potential. 4 The impact Stop Smoking E Cigarettes CardioSmart American College of Cardiology E cigs: More Dangerous Than We Thought Colorado Allergy & Asthma Centers, P.C. Difference Between E Cigarette and Vape Difference Between E Cigarette vs Vape Vaping releases toxic chemicals, including heavy metals, as well as ultrafine particles that go deep into the lungs. These increase the risk of heart and lung disorders.