Can Vaping Cause Stomach Issues? Vaping and Digestive Distress Advanced Food Intolerance Labs Nicotine Makes Me Feel Sick: How Nicotine's Chemicals Can Cause Discomfort The link between smoking, stomach pain and digestive problems Vaping releases toxic chemicals, including heavy metals, as well as ultrafine particles that go deep into the lungs. These increase the risk of heart and lung disorders. E cigarette, or Vaping Product, Use Associated Lung Injury (EVALI) Fact Sheets Yale Medicine