Toxicity, Chemistry, and Public Health Relevance of Emerging Nicotine Analog Vapes, Pods, and Pouches Chemical Research in Toxicology Full article: Disposable electronic cigarettes chemical composition and health effects of their use. A systematic review Known Health Effects of E Cigarette Use Kansas Health Institute Since their introduction in Europe in 2006 and the U.S. in 2007, the use of e cigarettes a.k.a., vapes has skyrocketed. A recent review from researchers in Australia found the results Health effects and known pathology associated with the use of E cigarettes ScienceDirect