Vape vs Cigarette Nicotine: How Many 5% Vape Puffs Equal One Cig? The nicotine content of many 2ml nicotine pods for multi pod devices is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. And if you are smoking How Many Puffs of Vape Equal a Cigarette? NHS gives definitive answer on how many cigarettes one disposable vape is equivalent to How Many Cigarettes Are in a Vape? Clear Answers Blakk Smoke